In This Issue
Less is More: The State of BCT
Patient Selection Criteria for APBI
Is Breast Cancer Overdiagnosed?
BrachyBytes Editorial Advisory Board

Deanna Attai, M.D.
Robert Kuske, M.D.
Jay Reiff, Ph.D.
Dan Scanderbeg, Ph.D.
Catheryn Yashar, M.D.
Vic Zannis, M.D.

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Medscape Medical News

January 2013 

Less is More: The State of Breast Conservation Therapy 

Deanna Attai, MD, FACS &
Jennifer Zook, MD

After decades of research, multiple randomized trials have shown  breast conservation therapy (BCT) to be equivalent to mastectomy, both in terms of survival and the risk of local recurrence.


Yet despite the advantages of BCT, several recent studies indicate an increase in national mastectomy rates in the past decade. Breast surgeon Deanna Jennifer Zook, MDAttai, MD, FACS, and radiation oncologist Jennifer Zook, MD, discuss the state of breast conservation therapy, factors behind the rising mastectomy rates, and how shortened forms of radiation therapy like accelerated partial breast irradiation (ABPI) may increase patient acceptance of BCT. Read more

Patient Selection Criteria for APBI   

BEST Forum, Volume 1

In this web-based presentation, Robert Kuske, MD, FAACE, examines the practical application of patient selection criteria for accelerated partial breast irradiation (APBI). Among the many benefits of APBI, he argues, is the therapy’s potential to increase the availability of breast conservation therapy.  

Dr. Robert Kuske Presentation
Watch BEST Forum: Volume 1 with Robert Kuske

Dr. Kuske discusses the origin and common misconceptions about the current ASTRO gudelines, as well as reviews emerging data for controversial subsets, such as women with ER negative tumors, DCIS and younger age (< 60 years).


Visit the BEST Forum website to watch additional presentations, as well as download slides, white papers and supporting clinical data.

Is Breast Cancer Overdiagnosed?  

from Medscape Medical News


According to a recent study published in the New England Journal of Medicine, an estimated 1.3 million American women had breast cancers that were “overdiagnosed” in the past 30 years.

Researchers examined trends in the incidence of early- and late-stage breast cancer in women 40 years and older from 1976 to 2008, concluding that overall about one-third of all breast cancers detected in the United States are overdiagnosed – primarily due to the advent of widespread mammography screening.

Many physicians, however, have questioned the authors’ methodology and central findings, arguing that the paper “‘is another in a long line of scientifically unsupportable attacks on mammography.'” Read more