In This Issue
Is Patient Selection Criteria for APBI Outdated?
BEST Forum: Patient Selection Criteria
New SAVI Data at 2014 ASBrS
BrachyBytes Editorial Advisory Board

Robert Kuske, M.D.

Jay Reiff, Ph.D.
Dan Scanderbeg, Ph.D.
Catheryn Yashar, M.D.
Vic Zannis, M.D.
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July 20-24, 2014
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American Brachytherapy Society

May 2014  

Is Patient Selection Criteria for APBI Outdated?
John Hayes, Jr., MS, MD    

Though long-term data are beginning to show that breast brachytherapy is as safe and effective as whole breast irradiation for a certain patient population, there remains a great deal of debate as to which patients fall into that category. Patient selection criteria from various medical societies, including the American Brachytherapy Society (ABS), American Society of Breast Surgeons (ASBrS) and American Society for Radiation Oncology (ASTRO), are varied on many characteristics, including age, tumor size and histology.

Perhaps most controversial are the ASTRO guidelines and the treatment of patients in the “cautionary” or “unsuitable” categories. Though numerous studies have been published showing no difference in outcomes with WBI or APBI for many of these patients, the guidelines have not been updated since the initial release in 2009 to reflect this emerging data.

Radiation oncologist John Hayes, Jr., MS, MD, of Gamma West Cancer Services, Salt Lake City, Utah, discusses his views on patient selection for breast brachytherapy, including recently published data and why he calls the ASTRO guidelines “quite dated.” Read more

BEST Forum: Patient Selection Criteria

In this web-based presentation, Robert Kuske, MD, FAACE, examines the practical application of patient selection criteria for APBI. Among the many benefits of APBI, he argues, is the therapy’s potential to increase the availability of breast conservation therapy.

Dr. Robert Kuske Presentation
Watch BEST Forum: Volume 1 with Robert Kuske

Dr. Kuske discusses the origin and common misconceptions about the current ASTRO gudelines, as well as reviews emerging data for controversial subsets, such as women with ER negative tumors, DCIS and younger age (< 60 years).


Visit the BEST Forum website to watch additional presentations, as well as download slides, white papers and supporting clinical data.

New Study: Minimal Long Term Side Effects with Strut-based Brachytherapy

At the 2014 meeting of the American Society of Breast Surgeons, researchers from the SAVI Collaborative Research Group presented the results of a study showing very low rates of toxicities with SAVI, even in patients with minimal space between the tumor cavity and skin.

“Our study confirms that strut-based brachytherapy allows us to treat any woman who is otherwise eligible for partial breast radiation with minimal risk of long-term toxicities,” said study co-author Emily Penman, MD. Read more