APBI with Brachytherapy Remains a Key Therapy for Patients with Early Stage Breast Cancer
Chirag Shah, MD is Associate Staff and Director of Clinical Research in the Department of Radiation Oncology and a member of the Taussig Cancer Institute at the Cleveland Clinic. He is also an Assistant Professor at Northeast Ohio Medical University. He is board certified by the American Board of Radiology and serves as the co-editor of the Radiation Oncology section of the American Society of Breast Surgeons BESAP program. Dr. Shah previously served on the American Brachytherapy Society APBI guidelines committee, is an editor for the journal Brachytherapy and is an author on over 100 peer-reviewed publications, reviews, editorials, and book chapters.
Do you believe that APBI with brachytherapy is relevant in 2017?
I do believe that brachytherapy based APBI remains not only relevant but a major consideration for appropriately selected patients. Brachytherapy offers the ability for patients to complete treatment in one week or less, which is still significantly shorter than hypo-fractionated whole breast irradiation. Additionally, the smaller target volume allows for less dose to the remaining breast tissue. Compared with other partial breast options, brachytherapy represents the technique with the longest follow-up and dosimetrically offers several advantages.
Have you seen a change in physician practice patterns for APBI since the ASTRO consensus change in late 2016?
I have not personally seen a substantial changes in practice patterns though it has only been a few months. I would expect use of APBI to increase based on the new guidelines which support treating patients 50 years or older and allows for low-risk DCIS in the suitable category. Additionally, with the publication of the GEC-ESTRO and Florence trials and the presentation of the IMPORT LOW trial, there is increased interest in partial breast approaches
Dr. Chirag Shah was recently featured on USA Radio Network,
perspectives on brachytherapy with one of the
argest talk radio networks in the country.