September 22, 2008

ALISO VIEJO, Calif. — At the 50th annual ASTRO meeting this week, Cianna Medical announced its new 6-1Mini version of the SAVI® applicator for delivery of radiation in breast conservation therapy.

The 6–1Mini, which is now in clinical use, is the smallest SAVI device in both length and width. The new model is designed to be used with the smallest of lumpectomy cavities. For example, it can treat tight cavities in the upper inner quadrant of the breast, an area that is often too small for balloon brachytherapy devices. The “6-1” in the model’s name refers to the applicator’s array of six peripheral catheters surrounding one central catheter.

SAVI is a single-entry, interstitial–type brachytherapy applicator that delivers radiation as part of breast conservation therapy. It is the only brachytherapy device that can customize the dose according to patient–specific anatomy. By more precisely targeting radiation therapy, SAVI treats the tissue where the cancer is most likely to recur, while minimizing the exposure of healthy tissue such as the skin, heart, lungs and ribs.

SAVI does not have the technical limitations experienced by balloon-based technologies. The open architecture, interstitial–like design of SAVI makes a five-day course of radiation available to twice as many women. Clinical studies have reported that 55% of the patients treated with SAVI were not eligible for balloon brachytherapy.

The 6–1Mini is one of several new enhancements made to SAVI being introduced this fall, including greater flexibility for increased patient comfort.

About Cianna Medical, Inc.
Cianna Medical, Inc. is a medical device company focused on women’s health and dedicated to the innovative treatment of early-stage breast cancer. The company manufactures and markets the SAVI breast brachytherapy applicator, for the delivery of radiation after lumpectomy surgery. The SAVI applicator allows contouring of the radiation dose, and is designed to make the benefits of accelerated partial breast irradiation available to a greater number of women. For more information about the company, call (toll-free) 866-920-9444 or visit http://www.SAVI.us.