How the SAVI Applicator Works

The SAVI® applicator combines the tissue-sparing dosimetry of interstitial brachytherapy with the single-entry ease of balloon brachytherapy. This strut-based approach is designed to maximize ease of use during placement while providing unparalleled dose customization.2




Placement

The closed applicator is inserted into the lumpectomy cavity through a single incision. Placement of the applicator can be done at the time of the lumpectomy or as a post-operative procedure.

Expansion

Once the applicator is placed in the cavity, rotation of the expansion tool deploys the catheters, conforming to the size of the cavity.

Radiation Delivery

The individual catheters are connected to an HDR afterloader for delivery of the radiation source. The multiple catheters offer more flexibility to sculpt the dose based on patient-specific anatomy. With the close proximity of the catheters to the targeted tissue, the radiation dose in each catheter can be modified to protect healthy tissues and organs, such as skin, lung and heart.

Typical treatment is twice a day for five days.



Removal

After the final treatment, the applicator is collapsed and removed.
The safety and effectiveness of the SAVI Applicator Kit for breast brachytherapy as a replacement for whole breast irradiation in the treatment of breast cancer has not been established.

The above information provides an overview of the SAVI applicator procedure. Refer to the Instructions For Use for complete information regarding use of the applicator and all warnings, contraindications, and safety information.